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Provisional standardization of hepcidin assays: creating a traceability chain with a primary reference material, candidate reference method and a commutable secondary reference materialDiepeveen, Laarakkers, Martos, Pawlak, Uğuz, Verberne, van Swelm, Klaver, de Haan, Pitts, Bansal, Abbas, Fillet, Lefebvre, Geurts-Moespot, Girelli, Castagna, Herkert, Itkonen, Olbina, Tomosugi, Westerman, Delatour, Weykamp, Swinkels. CCLM 2018; Epub
Sustained plasma hepcidin suppression and iron elevation by Anticalin-derived hepcidin antagonist in cynomolgus monkeyHohlbaum AM, Gille H, Trentmann S, Kolodziejczyk M, Rattenstetter B, Laarakkers CM, Katzmann G, Christian HJ, Andersen N, Allersdorfer A, Olwill SA, Meibohm B, Audoly LP, Swinkels DW, van Swelm RPL. Br J Pharmacol 2018; 175(7):1054-1065
Factors influencing the post-exercise hepcidin-25 response in elite athletesPeeling P, McKay AKA, Pyne DB, Guelfi KJ, McCormick RH, Laarakkers CM, Swinkels DW, Garvican-Lewis LA, Ross MLR, Sharma AP, Leckey JJ, Burke LM. Eur J Appl Physiol 2017;117(6):1233-1239.
Disrupted iron regulation in the brain and periphery in cocaine addictionErsche KD, Acosta-Cabronero J, Jones PS, Ziauddeen H, van Swelm RP, Laarakkers CM, Raha-Chowdhury R, Williams GB. Transl Psychiatry 2017;7(2):e1040.
Seven days of high carbohydrate ingestion does not attenuate post-exercise IL-6 and hepcidin levelsBadenhorst CE, Dawson B, Cox GR, Sim M, Laarakkers CM, Swinkels DW, Peeling P. Eur J Appl Physiol 2016;116(9):1715-24.
Live high, train low - influence on resting and post-exercise hepcidin levels.Govus AD, Peeling P, Abbiss CR, Lawler NG, Swinkels DW, Laarakkers CM, Thompson KG, Peiffer JJ, Gore CJ, Garvican-Lewis LA. Scand J Med Sci Sports 2016.
Renal handling of circulating and renal-synthesized hepcidin and its protective effects against hemoglobin-mediated kidney injuryvan Swelm RP, Wetzels JF, Verweij VG, Laarakkers CM, Pertijs JC, van der Wijst J, Thévenod F, Masereeuw R, Swinkels DW. J Am Soc Nephrol 2016; 27(9):2720-32
Underestimation of hepcidin concentration by time of flight mass spectrometry and competitive ELISA in hepcidin p.Gly71Asp heterozygotesvan der Vorm LN, van Meijel LJ, Lips J, Galesloot TE, Laarakkers CM, Swinkels DW. Clin Chem Lab Med 2016;54(5):e173-6.
Timing of post-exercise carbohydrate ingestion: influence on IL-6 and hepcidin responsesBadenhorst CE, Dawson B, Cox GR, Laarakkers CM, Swinkels DW, Peeling P. Eur J Appl Physiol 2015;115(10):2215-22.
Urinary hepcidin levels in iron-deficient and iron-supplemented piglets correlate with hepcidin hepatic mRNA and serum levels and with body iron statusStaroń R, Van Swelm RP, Lipiński P, Gajowiak A, Lenartowicz M, Bednarz A, Gajewska M, Pieszka M, Laarakkers CM, Swinkels DW, Starzyński RR. PLoS One 2015;10(8):e0136695.
Acute dietary carbohydrate manipulation and the subsequent inflammatory and hepcidin responses to exerciseBadenhorst CE, Dawson B, Cox GR, Laarakkers CM, Swinkels DW, Peeling P. Eur J Appl Physiol 2015;115(12):2521-30.
Engineered human lipocalin as an antibody mimetic: application to analysis of the small peptide hormone hepcidinGrebenchtchikov N, Geurts-Moespot AJ, Trentmann S, Andersen N, Bel Aiba RS, Allersdorfer A, Laarakkers CM, Sweep FC, Tjalsma H, Hohlbaum AM, Swinkels DW. Clin Chem 2014;60(6):897-9.
Effect of the antihepcidin Spiegelmer lexaptepid on inflammation-induced decrease in serum iron in humansvan Eijk LT, John AS, Schwoebel F, Summo L, Vauléon S, Zöllner S, Laarakkers CM, Kox M, van der Hoeven JG, Swinkels DW, Riecke K, Pickkers P. Blood 2014;124(17):2643-6.
Diurnal rhythm rather than dietary iron mediates daily hepcidin variationsSchaap CC, Hendriks JC, Kortman GA, Klaver SM, Kroot JJ, Laarakkers CM, Wiegerinck ET, Tjalsma H, Janssen MC, Swinkels DW. Clin Chem 2013;59(3):527-35.
Improved mass spectrometry assay for plasma hepcidin: detection and characterization of a novel hepcidin isoformLaarakkers CM, Wiegerinck ET, Klaver S, Kolodziejczyk M, Gille H, Hohlbaum AM, Tjalsma H, Swinkels DW. PLoS One 2013;8(10):e75518.
Inappropriately low hepcidin levels in patients with myelodysplastic syndrome carrying a somatic mutation of SF3B1Ambaglio I, Malcovati L, Papaemmanuil E, Laarakkers CM, Della Porta MG, Gallì A, Da Vià MC, Bono E, Ubezio M, Travaglino E, Albertini R, Campbell PJ, Swinkels DW, Cazzola M. Haematologica 2013;98(3):420-3.
Tubular reabsorption and local production of urine hepcidin-25Peters HP, Laarakkers CM, Pickkers P, Masereeuw R, Boerman OC, Eek A, Cornelissen EA, Swinkels DW, Wetzels JF. BMC Nephrol 2013;14:70.
Iron supplementation in suckling piglets: how to correct iron deficiency anemia without affecting plasma hepcidin levelsStarzyński RR, Laarakkers CM, Tjalsma H, Swinkels DW, Pieszka M, Styś A, Mickiewicz M, Lipiński P. PLoS One 2013;8(5):e64022.
Intra-individual variability of serum hepcidin-25 in haemodialysis patients using mass spectrometry and ELISAPeters HP, Rumjon A, Bansal SS, Laarakkers CM, van den Brand JA, Sarafidis P, Musto R, Malyszko J, Swinkels DW, Wetzels JF, Macdougall IC. Nephrol Dial Transplant 2012;27(10):3923-9.
Acute acetaminophen intoxication leads to hepatic iron loading by decreased hepcidin synthesisvan Swelm RP, Laarakkers CM, Blous L, Peters JG, Blaney Davidson EN, van der Kraan PM, Swinkels DW, Masereeuw R, Russel FG. Toxicol Sci 2012;129(1):225-33.
Hepcidin and hemoglobin content parameters in the diagnosis of iron deficiency in rheumatoid arthritis patients with anemiavan Santen S, van Dongen-Lases EC, de Vegt F, Laarakkers CM, van Riel PL, van Ede AE, Swinkels DW. Arthritis Rheum 2011;63(12):3672-80.
Reproducibility of and correspondence among different hepcidin forms in blood and urine and their relationships to iron status in healthy, male Guatemalan volunteers observed over 9 weeksSchuemann K, Solomons NW, Laarakkers CM, Romero-Abal ME, Kroll S, Weiss G, Swinkels DW. Ann Nutr Metab 2011;58(2):158-66.
Growth differentiation factor 15 in patients with congenital dyserythropoietic anaemia (CDA) type IICasanovas G, Swinkels DW, Altamura S, Schwarz K, Laarakkers CM, Gross HJ, Wiesneth M, Heimpel H, Muckenthaler MU. J Mol Med (Berl) 2011;89(8):811-6.
Mass spectrometry analysis of hepcidin peptides in experimental mouse modelsTjalsma H, Laarakkers CM, van Swelm RP, Theurl M, Theurl I, Kemna EH, van der Burgt YE, Venselaar H, Dutilh BE, Russel FG, Weiss G, Masereeuw R, Fleming RE, Swinkels DW. PLoS One 2011;6(3):e16762.
Hepcidin-25 is a marker of the response rather than resistance to exogenous erythropoietin in chronic kidney disease/chronic heart failure patientsvan der Putten K, Jie KE, van den Broek D, Kraaijenhagen RJ, Laarakkers C, Swinkels DW, Braam B, Gaillard CA. Eur J Heart Fail 2010 Sep;12(9):943-50.
Serum hepcidin-25 levels in patients with chronic kidney disease are independent of glomerular filtration ratePeters HP, Laarakkers CM, Swinkels DW, Wetzels JF. Nephrol Dial Transplant 2010;25(3):848-53.
Immunochemical and mass-spectrometry-based serum hepcidin assays for iron metabolism disordersKroot JJ, Laarakkers CM, Geurts-Moespot AJ, Grebenchtchikov N, Pickkers P, van Ede AE, Peters HP, van Dongen-Lases E, Wetzels JF, Sweep FC, Tjalsma H, Swinkels DW. Clin Chem 2010;56(10):1570-9.
Hepcidin serum levels and resistance to recombinant human erythropoietin therapy in haemodialysis patientsCosta E, Swinkels DW, Laarakkers CM, Rocha-Pereira P, Rocha S, Reis F, Teixeira F, Miranda V, do Sameiro Faria M, Loureiro A, Quintanilha A, Belo L, Santos-Silva A. Acta Haematol 2009;122(4):226-9.
Hepcidin levels in acute kidney injury following cardiopulmonary bypass graftingLaarakkers CM, Wetzels JF, Swinkels DW. Am J Kidney Dis 2009;54(5):979; author reply 980.
Hepcidin levels in acute kidney injury following cardiopulmonary bypass graftingLaarakkers CM, Wetzels JF, Swinkels DW. Am J Kidney Dis 2009;54(5):979; author reply 980.
Hepcidin levels in patients with renal diseasePeters HP, Laarakkers CM, Wetzels JF, Swinkels DW. Kidney Int 2009;76(6):680; author reply 680-1.
Regulation of serum hepcidin levels in sickle cell diseaseKroot JJ, Laarakkers CM, Kemna EH, Biemond BJ, Swinkels DW. Haematologica 2009;94(6):885-7.
Assessment of urinary concentrations of hepcidin provides novel insight into disturbances in iron homeostasis during malarial infectionde Mast Q, Nadjm B, Reyburn H, Kemna EH, Amos B, Laarakkers CM, Silalye S, Verhoef H, Sauerwein RW, Swinkels DW, van der Ven AJ. J Infect Dis 2009;199(2):253-62.
(Pre)analytical imprecision, between-subject variability, and daily variations in serum and urine hepcidin: implications for clinical studiesKroot JJ, Hendriks JC, Laarakkers CM, Klaver SM, Kemna EH, Tjalsma H, Swinkels DW. Anal Biochem 2009;389(2):124-9.
Serum hepcidin levels are innately low in HFE-related haemochromatosis but differ between C282Y-homozygotes with elevated and normal ferritin levelsvan Dijk BA, Laarakkers CM, Klaver SM, Jacobs EM, van Tits LJ, Janssen MC, Swinkels DW. Br J Haematol 2008;142(6):979-85.
Advances in quantitative hepcidin measurements by time-of-flight mass spectrometrySwinkels DW, Girelli D, Laarakkers C, Kroot J, Campostrini N, Kemna EH, Tjalsma H. PLoS One 2008;3(7):e2706.
Novel urine hepcidin assay by mass spectrometryKemna E, Tjalsma H, Laarakkers C, Nemeth E, Willems H, Swinkels D. Blood 2005;106(9):3268-70.
